SCHEMBL9316655

SCHEMBL9316655

O=C(O)C1=C(C(=O)O)CC(Cl)=CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PYGM P11217 1/20 0.32
GPR17 Q13304 1/20 0.31
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
TPMT P51580 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31518852 0.73 PYGM (0.32) PYGMTPMT
SCHEMBL9580700 0.71 PYGM (0.31) PYGM
SCHEMBL31518881 0.68 CA1 (0.32)
SCHEMBL2296442 0.68
SCHEMBL11430568 0.68 FFAR3 (0.36) PYGMALOX15TSHR
SCHEMBL890639 0.66 PYGM (0.52) PYGMALOX15TSHR
SCHEMBL27450172 0.61 GABRR1 (0.35) PYGMTSHR
SCHEMBL4827017 0.60 PYGM (0.33) PYGM
SCHEMBL25695033 0.59 PYGM (0.32) PYGM
SCHEMBL30225424 0.59 CYP1A2 (0.48) ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322954-A Synthesis of 4-substituted phthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1994-06-21 US disclosed