Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.56 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198443 | 0.91 | LTB4R (0.54) | LTB4RCYSLTR2CYSLTR1LTB4R2 | |
| SCHEMBL8957289 | 0.86 | CYSLTR2 (0.55) | LTB4RCYSLTR2CYSLTR1LTB4R2LMNA | |
| SCHEMBL8941565 | 0.77 | LTB4R (0.56) | LTB4RCYSLTR2CYSLTR1LTB4R2LMNA | |
| SCHEMBL8957143 | 0.76 | LTB4R (0.55) | LTB4RCYSLTR2CYSLTR1LTB4R2LMNA | |
| SCHEMBL8957166 | 0.76 | CYSLTR2 (0.66) | LTB4RCYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL9317125 | 0.76 | CYSLTR2 (0.51) | LTB4RCYSLTR2CYSLTR1LTB4R2LMNA | |
| SCHEMBL8583488 | 0.72 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8957057 | 0.71 | LTB4R (0.46) | LTB4RCYSLTR2CYSLTR1LTB4R2PPARG | |
| SCHEMBL8957215 | 0.70 | CYSLTR2 (0.56) | LTB4RCYSLTR2CYSLTR1LMNACYP1A2 | |
| SCHEMBL8586491 | 0.69 | LTB4R (0.58) | LTB4RPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593478-A1 | LEUKOTRIENE B 4? ANTAGONISTS. | SEARLE & CO (US) | 1994-04-27 | — | — | EP | disclosed |