Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317104 | 0.83 | PPARG (0.44) | LMNAPPARGPPARAPTPN1FFAR1 | |
| SCHEMBL9370917 | 0.83 | MAPT (0.52) | LMNAPPARGPPARAMAPTTHRB | |
| SCHEMBL9316790 | 0.82 | PPARG (0.43) | PPARGPPARAPTPN1MAPTFFAR1 | |
| SCHEMBL9721218 | 0.81 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL170065 | 0.80 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL4283015 | 0.80 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL6531845 | 0.80 | PPARG (0.61) | PPARGPPARAFFAR1 | |
| SCHEMBL9316742 | 0.79 | KDM4E (0.48) | LMNAPPARGPPARAMAPTFFAR1 | |
| SCHEMBL9721160 | 0.79 | PPARG (0.54) | PPARGPPARAMAPTFFAR1KDM4E | |
| SCHEMBL9721163 | 0.79 | PPARG (0.54) | PPARGPPARAMAPTFFAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330998-A | Anticholesterol agents | PFIZER INC. (US) | 1994-07-19 | — | — | US | disclosed |