Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.59 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316242 | 1.00 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL9316759 | 0.94 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL9316248 | 0.94 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Glutamic Acid SCHEMBL11725715 | 0.92 | SLC1A1 (0.51) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL27626877 | 0.90 | SLC1A1 (0.66) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL8129688 | 0.90 | SLC1A1 (0.66) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL11387995 | 0.84 | SLC7A5 (0.51) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL11664133 | 0.84 | SLC1A1 (0.41) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| Hydrochloric Acid SCHEMBL8129682 | 0.81 | SLC1A1 (0.64) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 | |
| SCHEMBL4304049 | 0.80 | SLC1A1 (0.71) | SLC1A1SLC1A3SLC1A2SLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625141-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY. | BLACK JAMES FOUNDATION (GB) | 1994-11-23 | — | — | EP | disclosed |
| WO-1993014066-A1 | AMINO ACID DERIVATIVES WITH ANTICHOLECYSTOKININ ACTIVITY | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-07-22 | — | — | WO | disclosed |