Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.66 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.66 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626877 | 1.00 | SLC1A1 (0.66) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL9316751 | 0.90 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL9316242 | 0.90 | SLC1A1 (0.59) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL27647034 | 0.88 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| Hydrochloric Acid SCHEMBL8129682 | 0.88 | SLC1A1 (0.64) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL27282304 | 0.88 | SLC1A3 (0.52) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL4304049 | 0.84 | SLC1A1 (0.71) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL12656179 | 0.83 | LTA4H (0.60) | SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL9316248 | 0.83 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI | |
| SCHEMBL9316759 | 0.83 | SLC1A1 (0.50) | SLC1A1SLC1A3SLC1A2SLC7A5ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0667859-B1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | ANORMED INC (CA) | 2000-08-23 | — | — | EP | disclosed |
| US-5679778-A | FOR FORMING CONJUGATES WITH MACROMOLECULES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0667859-A1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010149-A1 | MOLECULE LABELLING USING 2-HYDRANINOPYRIDINE DERIVATIVES | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1994-05-11 | — | — | WO | disclosed |