Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074477 | 0.91 | TDP1 (0.53) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL572190 | 0.85 | TDP1 (0.58) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL2776011 | 0.85 | MAPT (0.58) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL14467404 | 0.85 | TDP1 (0.58) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL2929031 | 0.84 | TDP1 (0.62) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL30989211 | 0.84 | TDP1 (0.62) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL9820329 | 0.83 | TDP1 (0.61) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL11494839 | 0.82 | MAPT (0.56) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL28127450 | 0.82 | TDP1 (0.55) | TDP1TSHRMAPTLMNAALDH1A1 | |
| SCHEMBL4857085 | 0.80 | TDP1 (0.53) | TDP1TSHRMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | claimed |
| US-5276132-A | Polyamic acid or polyimide having a steroidal skeleton providing a pretilt angle of 3 to 90 degrees; SBE(super twisted birefringence effect) and SH(super homeotropic) devices | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-01-04 | — | — | US | disclosed |