Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317025 | 0.87 | TP53 (0.39) | ALDH1A1HSD17B10NPSR1ATMGAA | |
| SCHEMBL9317102 | 0.85 | HPGD (0.43) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL9316984 | 0.83 | NPC1 (0.49) | ALDH1A1KDM4EKMT2ACA2NPC1 | |
| SCHEMBL3652880 | 0.77 | MAP4K4 (0.53) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL14972574 | 0.77 | MAP4K4 (0.53) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL9620615 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL3650360 | 0.77 | NPSR1 (0.59) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL8536043 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL18176014 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 | |
| SCHEMBL31396725 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4EKDM4CHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356440-A | Fiber-reactive dyes containing only one sulfo group | CIBA-GEIGY CORPORATION (US) | 1994-10-18 | — | — | US | disclosed |