Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6718038 | 0.86 | ALDH1A1 (0.56) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL6725312 | 0.86 | BLM (0.56) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL6725308 | 0.86 | BLM (0.56) | BLMKDM4EMAPTPTGS2MEN1 | |
| Water SCHEMBL11322500 | 0.85 | CYP1A2 (0.55) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL11600299 | 0.75 | ALDH1A1 (0.57) | BLMKDM4EMAPTPTGS2MEN1 | |
| Hydrochloric Acid SCHEMBL11602622 | 0.74 | ALDH1A1 (0.56) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL9316955 | 0.71 | MEN1 (0.39) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL6718046 | 0.69 | HPGD (0.56) | BLMKDM4EMAPTPTGS2MEN1 | |
| SCHEMBL4406628 | 0.67 | CYP2A6 (0.46) | MAPTUSP2CYP1A2CYP3A4GAA | |
| SCHEMBL11558120 | 0.67 | KDM4E (0.54) | BLMKDM4EMAPTPTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484437-A4 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | SEARLE & CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0484437-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. Searle & Co. (US) | 1992-05-13 | — | — | EP | claimed |