SCHEMBL9317006

SCHEMBL9317006

C=C(C)C(=O)OCCCCCCS(=O)(=O)c1ccc(C=Cc2ccc(N(C)C[C@H](C)CC)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 2/20 0.33
THRA P10827 1/20 0.33
PLA2G2C Q5R387 1/20 0.32
ABCB1 P08183 8/20 0.31
ABCC1 P33527 8/20 0.31
ABCG2 Q9UNQ0 7/20 0.31
MMP1 P03956 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9662199 1.00 TSHR (0.36) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9317808 0.89 TSHR (0.36) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9318819 0.88 TSHR (0.35) TSHRPOLBTHRBTHRAABCB1
SCHEMBL9318829 0.88 TSHR (0.35) TSHRPOLBTHRBTHRAABCB1
SCHEMBL9317157 0.85 POLB (0.40) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9317154 0.85 POLB (0.40) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9317704 0.83 POLB (0.45) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9317163 0.83 TSHR (0.37) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9316914 0.81 ALDH1A1 (0.33) POLBMMP1
SCHEMBL9316911 0.81 ALDH1A1 (0.33) POLBMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed