⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469248 | 0.80 | CA1 (0.31) | — | |
| SCHEMBL93135 | 0.75 | — | — | |
| SCHEMBL3710180 | 0.71 | — | — | |
| SCHEMBL41939 | 0.67 | — | — | |
| SCHEMBL7966489 | 0.65 | CA1 (0.32) | — | |
| SCHEMBL5254695 | 0.63 | CA1 (0.31) | — | |
| SCHEMBL27267 | 0.62 | — | — | |
| SCHEMBL4506753 | 0.62 | MGLL (0.36) | — | |
| SCHEMBL93284 | 0.59 | — | — | |
| SCHEMBL28319462 | 0.58 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426488-B1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEM IND LTD (JP) | 2016-04-20 | — | — | EP | disclosed |
| EP-2426123-B1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEM IND LTD (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8663990-B2 | Measurement method utilizing internal standard substance | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-04 | — | — | US | disclosed |
| US-8546586-B2 | Pyrazole-based cyanine dye containing quaternary ammonium cation | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2013-10-01 | — | — | US | disclosed |
| EP-2426488-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2426123-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | Wako Pure Chemical Industries, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046474-A1 | PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| US-20120043207-A1 | MEASUREMENT METHOD UTILIZING INTERNAL STANDARD SUBSTANCE | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2012-02-23 | — | — | US | disclosed |
| EP-2215085-A2 | PYRIDINE AND PYRAZINE DERIVATIVES USEFUL IN THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | AstraZeneca AB (SE) | 2010-08-11 | — | — | EP | disclosed |
| US-20100075942-A1 | N-PHENYL-4-PYRIDIN-2-YL-BENZAMIDE DERIVATIVES AS HISTONE DEACYLASE (HDAC) INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB | 2010-03-25 | — | — | US | disclosed |
| EP-0759432-A1 | Use of medicaments containing 3,4-diaryl furans and analogs thereof for treating a skin-related condition | G.D. SEARLE & CO. (US) | 1997-02-26 | — | — | EP | disclosed |
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0679157-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994015932-A1 | NOVEL 3,4-DIARYL THIOPHENES AND ANALOGS THEREOF HAVING USE AS ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1994-07-21 | — | — | WO | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| US-3931268-A | Methylhydrazinomethyl-substituted benzoic acid amides | HOFFMANN-LA ROCHE INC. (US) | 1976-01-06 | — | — | US | disclosed |