Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879704 | 0.81 | — | — | |
| Trifluoroacetic Acid SCHEMBL5264519 | 0.78 | FKBP5 (0.64) | FKBP5NOTUMCES1SCN8ASCN10A | |
| Uracil SCHEMBL29594408 | 0.74 | CRBN (0.68) | CRBNNOTUMCES1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL30967251 | 0.68 | HRH4 (0.43) | CES1DPP4KCNH2DPP7HRH4 | |
| Trifluoroacetic Acid SCHEMBL4627267 | 0.68 | HRH4 (0.43) | CES1DPP4KCNH2DPP7HRH4 | |
| Trifluoroacetic Acid SCHEMBL29522152 | 0.68 | HRH4 (0.40) | HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL5887706 | 0.65 | — | — | |
| Trifluoroacetic Acid SCHEMBL29713388 | 0.64 | HRH4 (0.35) | CES1HRH4HRH3 | |
| Trifluoroacetic Acid SCHEMBL29009901 | 0.64 | CYP2C9 (0.46) | CES1HDAC6 | |
| Trifluoroacetic Acid SCHEMBL15391360 | 0.63 | HRH4 (0.32) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-A1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII b?III a? RECEPTOR. | GENENTECH INC (US) | 1994-08-17 | — | — | EP | disclosed |