SCHEMBL9317307

SCHEMBL9317307

C=C(C)C(=O)OCCSc1ccc(N=Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.37
POLB P06746 2/20 0.37
MAPT P10636 6/20 0.35
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
RECQL P46063 2/20 0.35
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CA12 O43570 2/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317311 1.00 CYP2D6 (0.37) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL9317054 0.91 POLB (0.41) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL9317052 0.91 POLB (0.41) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL1462713 0.88 CA2 (0.40) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL9317079 0.87 CA2 (0.34) POLBMAPTTDP1TSHRCA12
SCHEMBL9317074 0.87 CA2 (0.34) POLBMAPTTDP1TSHRCA12
SCHEMBL9318518 0.86 HTR2A (0.37) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL9661820 0.86 HTR2A (0.37) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL810993 0.84 CA2 (0.37) CYP2D6POLBMAPTALDH1A1SMN1; SMN2
SCHEMBL13696518 0.83 CA2 (0.49) CYP2D6POLBMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed