Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 3/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651524 | 0.78 | MAOB (0.44) | CES1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL18013302 | 0.77 | ABCC4 (0.43) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL653617 | 0.74 | MAPT (0.39) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL654275 | 0.74 | MAPT (0.39) | MEN1KMT2ACDC25BS100A4LMNA | |
| SCHEMBL3294825 | 0.73 | TDP1 (0.42) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL652977 | 0.73 | ABCC4 (0.42) | GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL655918 | 0.72 | LMNA (0.38) | MEN1THRBKMT2AGAALMNA | |
| Hydrochloric Acid SCHEMBL4505546 | 0.72 | TDP1 (0.41) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL655182 | 0.71 | CYP19A1 (0.40) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL1404621 | 0.70 | GRM5 (0.48) | TDP1TDP2NSD2ABL1PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292735-A | Cyclic amide derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5179093-A | Viricides | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |