Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.35 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763417 | 0.84 | ALDH1A1 (0.35) | POLBNPSR1L3MBTL1KDM4EMEN1 | |
| SCHEMBL16026595 | 0.82 | MEN1 (0.37) | KDM4EMEN1KMT2AALDH1A1CHRNB2 | |
| SCHEMBL10154480 | 0.80 | HRH3 (0.46) | BLMPOLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL13472662 | 0.79 | ALDH1A1 (0.46) | BLMPOLBNPSR1L3MBTL1MEN1 | |
| SCHEMBL4682780 | 0.79 | BLM (0.44) | BLMPOLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL4723629 | 0.79 | PIK3CD (0.47) | KDM4EKMT2AALDH1A1EPHX2 | |
| SCHEMBL4682783 | 0.79 | BLM (0.44) | BLMPOLBNPSR1L3MBTL1KDM4E | |
| SCHEMBL4724913 | 0.79 | PIK3CD (0.47) | KDM4EKMT2AALDH1A1EPHX2 | |
| SCHEMBL946054 | 0.77 | KDM4E (0.38) | BLMKDM4EALDH1A1TP53 | |
| SCHEMBL20621109 | 0.77 | KDM4E (0.56) | BLMPOLBNPSR1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | claimed |