SCHEMBL9317435

SCHEMBL9317435

C=C(C)C(=O)OCCOc1ccc(/N=N/c2ccc(S(C)(=O)=O)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.48
APEX1 P27695 1/20 0.48
HTT P42858 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
PPARA Q07869 12/20 0.39
PPARG P37231 4/20 0.39
ALDH1A1 P00352 1/20 0.38
CYP1A2 P05177 1/20 0.38
PPARD Q03181 4/20 0.38
GPR119 Q8TDV5 1/20 0.37
THRB P10828 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317441 1.00 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317377 0.93 HTT (0.58) POLBAPEX1HTTTDP1PPARA
SCHEMBL20828630 0.89 POLB (0.57) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317035 0.87 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317039 0.87 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317383 0.85 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL9317387 0.85 POLB (0.48) POLBAPEX1HTTTDP1PPARA
SCHEMBL20828629 0.84 POLB (0.52) POLBAPEX1HTTTDP1PPARA
SCHEMBL5332386 0.84 TDP1 (0.52) POLBAPEX1HTTTDP1PPARA
SCHEMBL5332382 0.84 TDP1 (0.52) POLBAPEX1HTTTDP1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed