Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9317473 | 1.00 | THRB (0.53) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL9317370 | 0.93 | THRB (0.63) | THRBPPARAALDH1A1PPARGPPARD | |
| SCHEMBL9317373 | 0.93 | THRB (0.63) | THRBPPARAALDH1A1PPARGPPARD | |
| SCHEMBL31606936 | 0.89 | THRB (0.62) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL31606932 | 0.89 | THRB (0.62) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL26750097 | 0.89 | THRB (0.62) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL14926751 | 0.89 | THRB (0.62) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL31606928 | 0.89 | THRB (0.62) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL9317404 | 0.87 | THRB (0.54) | THRBPPARAALDH1A1TSHRCYP3A4 | |
| SCHEMBL25338886 | 0.87 | TSHR (0.58) | THRBPPARAALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5322986-A | Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby | EASTMAN KODAK COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-5157541-A | Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode | EASTMAN KODAK COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| US-5075796-A | OPTICAL ARTICLE FOR MULTICOLOR IMAGING | EASTMAN KODAK COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0422725-A2 | High x(2) optical article | EASTMAN KODAK COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| EP-0422723-A2 | Optical article for reflection modulation | EASTMAN KODAK COMPANY (US) | 1991-04-17 | — | — | EP | disclosed |
| US-4948225-A | REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING | EASTMAN KODAK COMPANY (US) | 1990-08-14 | — | — | US | disclosed |