Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768675 | 0.89 | MEN1 (0.62) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL31497682 | 0.89 | MEN1 (0.62) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL7535051 | 0.87 | ESR1 (0.75) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL25039218 | 0.85 | KMT2A (0.52) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL10838797 | 0.85 | CYP19A1 (0.64) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL35881 | 0.84 | ESR1 (0.70) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL14910456 | 0.84 | ESR1 (0.70) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL11579850 | 0.83 | SMN1; SMN2 (0.45) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL4062666 | 0.81 | KMT2A (0.82) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL16144309 | 0.81 | KMT2A (0.82) | ESR1ESR2ALDH1A1CYP3A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073702-A1 | PROCESS FOR PREPARING AROMATIC AMINES FROM ARYL CHLORIDES | BASF SE (DE) | 2025-04-10 | — | — | WO | disclosed |
| US-9434705-B2 | L-setastine hydrochloride and preparation method thereof | ANHUI QINGYUN PHARMACEUTICAL & CHEMICAL CO., LTD. (CN) | 2016-09-06 | — | — | US | disclosed |
| US-20140296517-A1 | L-Setastine Hydrochloride and Preparation Method Thereof | ANHUI QINGYUN PHARMACEUTICAL | 2014-10-02 | — | — | US | disclosed |
| US-5288848-A | Reacting mono- and dihalogenated aromatics with alkali sulfide ; low corrosion during processing | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |
| US-4929747-A | POLYMERIZATION CATALYSTS | NIPPON OIL & FATS COMPANY, LTD. (JP) | 1990-05-29 | — | — | US | disclosed |
| US-4760127-A | Reacting dihalogen aromatics and alkali metal sulfide in presence of a monohalogen compound and a monomercapto compound | BAYER AG (DE) | 1988-07-26 | — | — | US | disclosed |
| EP-0214471-A1 | Process for the preparation of high molecular weight polyarylene sulfides which can be reticulated | BAYER AG (DE) | 1987-03-18 | — | — | EP | disclosed |
| US-3989611-A | HALOGENATED HYDROCARBON CATALYST | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296517-A1 | L-Setastine Hydrochloride and Preparation Method Thereof | HRH4, HRH1, HRH3 | ESR1 2122/4885ESR2 2715/4885ALDH1A1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.