Phthalic Acid

Phthalic Acid

SCHEMBL9317638

CC1CCOC(=O)CCCCC(=O)O1.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.41

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA9 Q16790 2/20 0.41
ALDH1A1 P00352 7/20 0.38
ALOX15 P16050 1/20 0.38
KDM4E B2RXH2 4/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
HTT P42858 1/20 0.38
RCE1 Q9Y256 1/20 0.38
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ABCC1 P33527 2/20 0.35
KMT2A Q03164 1/20 0.34
FABP4 P15090 1/20 0.33
MYC P01106 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL11500372 0.86 ALDH1A1 (0.40) CA1CA9ALDH1A1ALOX15KDM4E
Phthalic Acid SCHEMBL31168189 0.82 ALDH1A1 (0.52) CA1CA9ALDH1A1ALOX15KDM4E
Phthalic Acid SCHEMBL11042802 0.82 ALDH1A1 (0.52) CA1CA9ALDH1A1ALOX15KDM4E
SCHEMBL9242780 0.82 CA1 (0.59) CA1CA9ALDH1A1KMT2A
Phthalic Acid SCHEMBL22799197 0.81 CA1 (0.57) CA1CA9ALDH1A1ALOX15KDM4E
SCHEMBL11052468 0.81 CA1 (0.57) CA1CA9ALDH1A1MAPTKMT2A
SCHEMBL10346521 0.81 CA1 (0.57) CA1CA9ALDH1A1MAPTKMT2A
SCHEMBL3883815 0.79 CA1 (0.59) CA1CA9ALDH1A1MAPTKMT2A
Phthalic Acid SCHEMBL11604075 0.77 ALDH1A1 (0.45) CA1CA9ALDH1A1ALOX15KDM4E
Phthalic Acid SCHEMBL10624085 0.76 HTT (0.36) ALDH1A1ALOX15KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5364956-A Dehydration esterification MATSUMOTO SATOSHI (JP) 1994-11-15 US disclosed