SCHEMBL9317685

SCHEMBL9317685

OC(Cl)(CCl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 4/20 0.43
CYP2C9 P11712 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 4/20 0.36
KCNN4 O15554 1/20 0.36
HIF1A Q16665 2/20 0.35
MAPK1 P28482 2/20 0.35
CYP2D6 P10635 2/20 0.35
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.35
TRPA1 O75762 1/20 0.34
GSK3B P49841 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
ALOX15 P16050 1/20 0.34
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476372 0.80 TSHR (0.48) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
Hydrochloric Acid SCHEMBL11308929 0.78 TSHR (0.46) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL5163676 0.78 TSHR (0.46) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL3046939 0.78 TAAR1 (0.48) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL5161709 0.78 TSHR (0.46) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL4295864 0.78 TSHR (0.46) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL8764225 0.77 CYP2C19 (0.56) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL9661051 0.77 CYP2C9 (0.47) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
Hydrochloric Acid SCHEMBL6219522 0.76 TAAR1 (0.46) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2
SCHEMBL30381753 0.75 CYP2C19 (0.43) TSHRCYP1A2CYP2C19CYP2C9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105087662-A Method for producing chiral chlorphenyl chlorethanol by use of yeast UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-25 CN disclosed
CN-105063103-A Method for producing chiral phenyl dichloroethanol with molds UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-11-18 CN disclosed
US-5376684-A Aminobutyric acid antagonist; antiepileptic agent CIBA-GEIGY CORPORATION (US) 1994-12-27 US disclosed
US-3966900-A INSECTICIDES AIRWICK INDUSTRIES, INC. (US) 1976-06-29 US disclosed