SCHEMBL9317811

SCHEMBL9317811

C=CC(=O)OCCOc1ccc(C=Cc2ccc(S(=O)(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.64
PPARA Q07869 5/20 0.47
ALDH1A1 P00352 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43
CHRNA10 Q9GZZ6 1/20 0.43
CHRNA9 Q9UGM1 1/20 0.43
PPARG P37231 3/20 0.42
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALB P02768 1/20 0.41
HTR2A P28223 1/20 0.41
LTA4H P09960 1/20 0.40
AKR1B10 O60218 1/20 0.39
AKR1B1 P15121 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9317806 1.00 THRB (0.64) THRBPPARAALDH1A1CHRNB4CHRNA3
SCHEMBL9317404 0.93 THRB (0.54) THRBPPARAALDH1A1CHRNB4CHRNA3
SCHEMBL372589 0.88 THRB (0.67) THRBALDH1A1GAANPSR1CA12
SCHEMBL372590 0.88 THRB (0.67) THRBALDH1A1GAANPSR1CA12
SCHEMBL12769636 0.87 THRB (0.52) THRBALDH1A1GAANPSR1AKR1B10
SCHEMBL9317373 0.87 THRB (0.63) THRBPPARAALDH1A1PPARGGAA
SCHEMBL9317370 0.87 THRB (0.63) THRBPPARAALDH1A1PPARGGAA
SCHEMBL12735508 0.85 THRB (0.71) THRBPPARAALDH1A1PPARGALB
SCHEMBL9318531 0.85 THRB (0.56) THRBPPARAALB
SCHEMBL9318533 0.85 THRB (0.56) THRBPPARAALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322986-A Methods for preparing polymer stripe waveguides and polymer stripe waveguides prepared thereby EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
US-5157541-A Support with dielectric, reflection metal, polymeric electrooptical layers, couterelectrode EASTMAN KODAK COMPANY (US) 1992-10-20 US disclosed
US-5075796-A OPTICAL ARTICLE FOR MULTICOLOR IMAGING EASTMAN KODAK COMPANY (US) 1991-12-24 US disclosed
EP-0422725-A2 High x(2) optical article EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
EP-0422723-A2 Optical article for reflection modulation EASTMAN KODAK COMPANY (US) 1991-04-17 EP disclosed
US-4948225-A REFLECTIVE METAL LAYER, DIELECTRICS, PROTECTIVE COATING EASTMAN KODAK COMPANY (US) 1990-08-14 US disclosed