Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411862 | 1.00 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL1555518 | 0.89 | ABCB1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL1554872 | 0.89 | ABCB1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL1554868 | 0.89 | ABCB1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL10414190 | 0.88 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7424413 | 0.88 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL10414188 | 0.88 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7413529 | 0.86 | POLB (0.43) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7413567 | 0.86 | POLB (0.43) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL15564386 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559793-A4 | — | — | 1994-04-27 | — | — | EP | disclosed |
| EP-0559793-A1 | HIV PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-15 | — | — | EP | disclosed |