Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202832 | 0.83 | RECQL (0.42) | EGLN1ALDH1A1KDM4ERECQLHSD17B10 | |
| SCHEMBL4892460 | 0.73 | CYP2D6 (0.33) | — | |
| SCHEMBL13989344 | 0.73 | CYP2D6 (0.33) | — | |
| SCHEMBL4892454 | 0.73 | CYP2D6 (0.33) | — | |
| SCHEMBL233413 | 0.68 | FAAH (0.55) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL21176794 | 0.66 | FAAH (0.53) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL21176786 | 0.66 | FAAH (0.53) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL21176784 | 0.66 | FAAH (0.53) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL21176788 | 0.66 | FAAH (0.53) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL28618934 | 0.66 | FAAH (0.58) | PLA2G2AFFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276048-A | 4-(1H-pyrrol-1-yl)imidazoles with angiotensin II antagonist activity | WARNER-LAMBERT COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5210211-A | 4-(1H-PYRROL-1-YL) IMIDAZOLES WITH ANGIOTENSION II ANTAGONIST ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1993-05-11 | — | — | US | disclosed |