SCHEMBL9318375

SCHEMBL9318375

CCc1cnc(C(=O)O)cc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASPH Q12797 12/20 0.56
KDM4E B2RXH2 11/20 0.56
KDM8 Q8N371 11/20 0.56
GABRP O00591 3/20 0.51
GABRD O14764 3/20 0.51
GABRA1 P14867 3/20 0.51
GABRB1 P18505 3/20 0.51
GABRG2 P18507 3/20 0.51
GABRB3 P28472 3/20 0.51
GABRA5 P31644 3/20 0.51
GABRA3 P34903 3/20 0.51
GABRA2 P47869 3/20 0.51
GABRB2 P47870 3/20 0.51
GABRA4 P48169 3/20 0.51
GABRE P78334 3/20 0.51
GABRA6 Q16445 3/20 0.51
GABRG1 Q8N1C3 3/20 0.51
GABRG3 Q99928 3/20 0.51
GABRQ Q9UN88 3/20 0.51
RIOX2 Q8IUF8 8/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19857498 0.85 GABRP (0.66) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL28265125 0.84 GABRP (0.45) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL11623407 0.81 GABRP (0.51) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL31220850 0.81 KDM4E (0.47) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL23674714 0.79 GABRP (0.50) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL6931483 0.79 GABRP (0.74) KDM4EGABRPGABRDGABRA1GABRB1
SCHEMBL23674678 0.79 GABRP (0.50) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL30100688 0.79 GABRP (0.50) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL1171098 0.77 KDM4E (0.67) ASPHKDM4EKDM8GABRPGABRD
SCHEMBL9318758 0.76 KDM4E (0.60) ASPHKDM4EKDM8GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP claimed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US claimed
EP-0281943-B1 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AG (DE) 1994-01-12 EP claimed
US-5143926-A Substituted pyridine-2,4-dicarboxylic acid compounds and methods of use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-01 US claimed
EP-0281943-A2 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-14 EP claimed
US-10590343-B2 Corrosion inhibitor composition for magnesium or magnesium alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2020-03-17 US disclosed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP disclosed
EP-3284847-A1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS Helmholtz-Zentrum Geesthacht Zentrum für Material- und Küstenforschung GmbH (DE) 2018-02-21 EP disclosed
US-20180044590-A1 Corrosion Inhibitor Composition for Magnesium or Magnesium Alloys Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbH (DE) 2018-02-15 US disclosed
US-5356909-A Substituted pyridine-2,4-dicarboxylic acid compounds and the use thereof and medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
EP-0281943-B1 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AG (DE) 1994-01-12 EP disclosed
US-5143926-A Substituted pyridine-2,4-dicarboxylic acid compounds and methods of use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-01 US disclosed
US-5004748-A Substituted pyridine-2,4-dicarboxylic acid derivatives and medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-02 US disclosed
EP-0281943-A2 Substituted pyridine-2,4-carboxylic acid derivatives, process for their preparation, their use as well as medicaments based on these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1988-09-14 EP disclosed