Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639267 | 0.88 | CTRC (0.54) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL9318310 | 0.85 | CYSLTR2 (0.51) | CTRCALDH1A1PPARGCYSLTR2CYSLTR1 | |
| SCHEMBL11521450 | 0.83 | KMT2A (0.53) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL21253070 | 0.81 | CTRC (0.48) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL14565994 | 0.80 | CTRC (0.50) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL568454 | 0.80 | CTRC (0.50) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL568643 | 0.80 | CTRC (0.50) | CTRCALDH1A1PPARGPTGESALOX5 | |
| SCHEMBL9318032 | 0.80 | CYSLTR2 (0.52) | CTRCPPARGCYSLTR2CYSLTR1PTGES | |
| SCHEMBL19717843 | 0.79 | KDM4E (0.56) | CTRCALDH1A1PPARGPTGESALOX5 | |
| Sebacic Acid SCHEMBL151731 | 0.79 | CTRC (0.58) | CTRCALDH1A1PPARGPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576603-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | disclosed |