Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.48 |
| ▸ | GPR4 | P46093 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434941 | 0.87 | AGTR1 (0.52) | AGTR1AGTR2GPR4 | |
| SCHEMBL9318419 | 0.87 | AGTR1 (0.46) | AGTR1AGTR2GPR4 | |
| SCHEMBL9320040 | 0.86 | — | — | |
| SCHEMBL9318617 | 0.86 | AGTR1 (0.48) | AGTR1AGTR2GPR4 | |
| SCHEMBL9434955 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2GPR4 | |
| SCHEMBL5434268 | 0.77 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9655652 | 0.77 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9318954 | 0.77 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9434990 | 0.77 | — | — | |
| SCHEMBL9318357 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5317023-A | 2-Phenyl-(imidazo(4,5-b)pyridyl-methyl-) derivatives; hypertensive agents; cognition activators | GLAXO GROUP LIMITED (GB) | 1994-05-31 | — | — | US | disclosed |
| WO-1992020679-A1 | BENZOFURAN DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |
| EP-0514197-A1 | Anti-hypertensive benzofuran derivatives substituted by N-imidazolyl-methyl groups which are condensed with optionally nitrogen containing, six-membered rings | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |