Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009199 | 0.87 | FFAR1 (0.53) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL28097226 | 0.81 | CNR1 (0.46) | ADRB2ADRB1ADRB3HDAC1HDAC8 | |
| SCHEMBL28262225 | 0.81 | CNR1 (0.46) | ADRB2ADRB1ADRB3HDAC1HDAC8 | |
| SCHEMBL1007564 | 0.81 | CNR2 (0.47) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL28809537 | 0.81 | CNR1 (0.46) | ADRB2ADRB1ADRB3HDAC1HDAC8 | |
| SCHEMBL9318967 | 0.78 | PARP10 (0.41) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7622732 | 0.78 | ADRB2 (0.41) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL14199087 | 0.77 | CYP1A2 (0.44) | MEN1KMT2ATDP1PARP10 | |
| SCHEMBL7622456 | 0.76 | CYP1A2 (0.42) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL18641735 | 0.76 | EPHX2 (0.54) | TDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5283262-A | Antiinflammatory, antiallergens | GLAXO GROUP LIMITED (GB) | 1994-02-01 | — | — | US | disclosed |
| US-5109023-A | For treating asthma, chronic bronchits, gastrointestinal disorders, anticoagulant, antiinflammatory agent and antiallergens | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| US-5099068-A | Antiulcer agents, beta-adrenoreceptors or bronchodilator agents for treatment of asthma | GLAXO GROUP LIMITED (GB) | 1992-03-24 | — | — | US | disclosed |
| US-4997986-A | Respiratory system disorders | GLAXO GROUP LIMITED (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0317206-A2 | Phenethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |