Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27862543 | 0.80 | TSHR (0.37) | HPGDTSHR | |
| SCHEMBL27596746 | 0.76 | TSHR (0.35) | HPGDTSHR | |
| SCHEMBL5643106 | 0.75 | ATM (0.35) | HPGDTSHR | |
| SCHEMBL1928774 | 0.75 | TSHR (0.34) | HPGDTSHR | |
| SCHEMBL10773593 | 0.73 | TSHR (0.40) | HPGDTSHR | |
| SCHEMBL12253207 | 0.71 | ADH1C (0.43) | TSHR | |
| SCHEMBL3139541 | 0.68 | ADH1C (0.36) | HPGDTSHR | |
| SCHEMBL1566319 | 0.68 | ADH1C (0.40) | TSHR | |
| SCHEMBL9767729 | 0.67 | ADH1C (0.39) | HPGDTSHR | |
| SCHEMBL8422500 | 0.66 | ATM (0.38) | HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353752-B1 | N-2, 3-butadienyl triaminoalkane derivatives | MERRELL DOW PHARMA (US) | 1994-01-05 | — | — | EP | disclosed |
| US-4935449-A | TREATING A MALARIAL INFECTION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-19 | — | — | US | disclosed |
| EP-0353752-A1 | N-2, 3-butadienyl triaminoalkane derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-02-07 | — | — | EP | disclosed |