Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.77 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | MYOC | Q99972 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | SRC | P12931 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | CDK2 | P24941 | 1/20 | 0.66 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318926 | 1.00 | TERT (0.82) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL31682981 | 0.90 | TERT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL29379310 | 0.90 | TERT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL34958 | 0.90 | TERT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL34959 | 0.90 | TERT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL25192703 | 0.87 | MAPT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL4973168 | 0.87 | MAPT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL31233153 | 0.87 | MAPT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL5508056 | 0.87 | MAPT (1.00) | TERTMAPTPTGS1PTGS2KMT2A | |
| SCHEMBL5574069 | 0.84 | MAPT (0.76) | TERTMAPTKMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195430-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | UAB RESEARCH FOUNDATION (US) | 2019-10-10 | — | — | WO | disclosed |
| EP-0629602-A1 | 3,4-Dihydroxychalcone derivatives | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5276058-A | Antiinflammatory agents | NIPPON HYPOX LABORATORIES INCORPORATED (JP) | 1994-01-04 | — | — | US | disclosed |