SCHEMBL9319110

SCHEMBL9319110

Nc1cccc(N)c1-c1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.52
IKBKB O14920 1/20 0.51
ALDH1A1 P00352 4/20 0.50
CYP3A4 P08684 3/20 0.50
HSD17B10 Q99714 3/20 0.50
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
KDM4E B2RXH2 2/20 0.48
NPC1 O15118 1/20 0.48
AR P10275 1/20 0.48
MAPT P10636 1/20 0.48
NFKB1 P19838 1/20 0.48
RAB9A P51151 1/20 0.48
GFER P55789 1/20 0.48
NFKB2 Q00653 1/20 0.48
RELA Q04206 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP1A1 P04798 1/20 0.48
CYP1B1 Q16678 1/20 0.48
GSTP1 P09211 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35312 0.91 CYP1A2 (0.52) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL9681001 0.90 IKBKB (0.53) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL2934548 0.89 ALOX5 (0.52) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL24432375 0.84 IKBKB (0.46) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL259164 0.84 GSTP1 (0.47) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL25799793 0.83 CYP1A1 (0.51) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL18903076 0.81 CYP3A4 (0.56) CYP1A2ALDH1A1CYP3A4HSD17B10HSD17B1
SCHEMBL1901543 0.81 GSTP1 (0.48) CYP1A2IKBKBALDH1A1CYP3A4HSD17B10
SCHEMBL31302869 0.80 CYP1A1 (0.49) CYP1A2ALDH1A1HSD17B10HSD17B1HSD17B2
SCHEMBL557231 0.80 GSTP1 (0.57) CYP1A2ALDH1A1CYP3A4HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112585145-B Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2023-09-29 CN disclosed
CN-112585145-A Polycyclic compound and organic light emitting device including the same 株式会社LG化学 2021-03-30 CN disclosed
US-5308523-A Butylene-ethylene-styrene terpolymer block copolymer TEXACO INC. (US) 1994-05-03 US disclosed