Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319299 | 0.95 | RARB (0.48) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9319177 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9318592 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9318857 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9318322 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9320728 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9318451 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9319170 | 0.94 | RARB (0.50) | RARBRARARARGHSD11B1MAPT | |
| SCHEMBL9318494 | 0.90 | MAPT (0.41) | RARBRARARARGMAPTNISCH | |
| SCHEMBL9318418 | 0.83 | TAAR1 (0.35) | NISCHALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292454-A | Trifluorotoluene compounds, and a liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-03-08 | — | — | US | disclosed |