Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320728 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9318451 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9318857 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9318592 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9319177 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9318322 | 1.00 | RARB (0.50) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9319299 | 0.98 | RARB (0.48) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9319147 | 0.94 | RARB (0.43) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9318494 | 0.88 | MAPT (0.41) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL9318692 | 0.83 | RARB (0.45) | RARBRARARARGHTR2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292454-A | Trifluorotoluene compounds, and a liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-03-08 | — | — | US | disclosed |