Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IGFBP3 | P17936 | 5/20 | 0.45 |
| ▸ | IGFBP5 | P24593 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IGFBP1 | P08833 | 1/20 | 0.41 |
| ▸ | IGFBP2 | P18065 | 1/20 | 0.41 |
| ▸ | IGFBP4 | P22692 | 1/20 | 0.41 |
| ▸ | IGFBP6 | P24592 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405037 | 0.87 | MGAM (0.63) | MGAMKDM4EKMT2AALOX15TDP1 | |
| SCHEMBL29411763 | 0.85 | MGAM (0.49) | MGAMKDM4EKMT2AIGFBP3IGFBP5 | |
| SCHEMBL26606765 | 0.85 | MGAM (0.49) | MGAMKDM4EKMT2AIGFBP3IGFBP5 | |
| SCHEMBL9220609 | 0.85 | MGAM (0.61) | MGAMKDM4EKMT2AALOX15TDP1 | |
| SCHEMBL950437 | 0.80 | MGAM (0.60) | MGAMKDM4EKMT2AALOX15TDP1 | |
| SCHEMBL20772073 | 0.78 | MGAM (0.53) | MGAMKDM4EKMT2AIGFBP5ALOX15 | |
| SCHEMBL2715968 | 0.78 | MGAM (0.53) | MGAMKDM4EKMT2AIGFBP5ALOX15 | |
| SCHEMBL2211860 | 0.78 | MGAM (0.58) | MGAMKDM4EKMT2AALOX15TDP1 | |
| SCHEMBL12501532 | 0.78 | MGAM (0.69) | MGAMKDM4EKMT2AALOX15TDP1 | |
| SCHEMBL28278979 | 0.76 | MGAM (0.60) | MGAMKDM4EKMT2AALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |
| US-5232918-A | Bactericides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |