Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12405037 | 0.93 | MGAM (0.63) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL12501532 | 0.88 | MGAM (0.69) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL14806709 | 0.86 | KMT2A (0.60) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL9319235 | 0.85 | MGAM (0.55) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL2715968 | 0.84 | MGAM (0.53) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL20772073 | 0.84 | MGAM (0.53) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL11639677 | 0.83 | MGAM (0.45) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL28278979 | 0.81 | MGAM (0.60) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL950437 | 0.81 | MGAM (0.60) | MGAMKDM4EALOX15TSHRTDP1 | |
| SCHEMBL2175934 | 0.80 | MGAM (0.64) | MGAMKDM4EALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394846-B1 | Organic photochromic compound | SEIKISUI CHEMICAL CO LTD (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5091535-A | ORGANIC PHOTOCHROMIC COMPOUND, A DIMER OF PYRIDO QUINOLINE | SEIKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0394846-A2 | Organic photochromic compound | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | disclosed |