Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATP4A | P20648 | 1/20 | 0.51 |
| ▸ | ATP4B | P51164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320767 | 0.86 | MEN1 (0.53) | MEN1KMT2AATP4AATP4B | |
| SCHEMBL9319306 | 0.85 | MEN1 (0.53) | MEN1KMT2AATP4AATP4B | |
| SCHEMBL9318536 | 0.78 | ATP4A (0.84) | ATP4AATP4B | |
| SCHEMBL9320011 | 0.78 | KDM4E (0.64) | ATP4AATP4BKDM4E | |
| SCHEMBL9319922 | 0.77 | ATP4A (0.61) | ATP4AATP4BKDM4E | |
| SCHEMBL19021085 | 0.73 | MEN1 (0.69) | MEN1KMT2AKDM4ELMNAGLA | |
| SCHEMBL31681091 | 0.72 | MEN1 (0.68) | MEN1KMT2AKDM4ELMNAGLA | |
| SCHEMBL774957 | 0.72 | ATP4A (0.61) | ATP4AATP4B | |
| SCHEMBL4721440 | 0.72 | MEN1 (0.68) | MEN1KMT2AKDM4ELMNAGLA | |
| SCHEMBL4319748 | 0.72 | CTNNB1 (0.57) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362743-A | Aminoquinoline derivatives | PFIZER INC. (US) | 1994-11-08 | — | — | US | disclosed |