SCHEMBL93194

SCHEMBL93194

C=CC(=O)OCCC[Si](OC(C)OCC)(OC(C)OCC)OC(C)OCC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
HPGD P15428 1/20 0.50
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.46
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 2/20 0.37
ATM Q13315 1/20 0.34
HCAR2 Q8TDS4 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3041893 0.89 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1806619 0.85 TSHR (0.49) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL133590 0.83 TSHR (0.53) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL10798534 0.83 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL6151296 0.81 TSHR (0.51) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL93435 0.80 TSHR (0.47) TSHRALDH1A1THRBLMNA
SCHEMBL27976546 0.80 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29959390 0.79 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL93561 0.79 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL29959469 0.78 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862806-B2 Plastic article for automotive glazing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2607413-B1 Plastic Substrate for Automotive Glazing and Its Repairing Method SHINETSU CHEMICAL CO (JP) 2017-06-21 EP disclosed
EP-2426175-B1 Plastic article for automotive glazing SHINETSU CHEMICAL CO (JP) 2014-07-23 EP disclosed
US-20130164539-A1 PLASTIC SUBSTRATE FOR AUTOMOTIVE GLAZING AND ITS REPAIRING METHOD KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-06-27 US disclosed
EP-2607413-A1 Plastic Substrate for Automotive Glazing and Its Repairing Method Shin-Etsu Chemical Co., Ltd. (JP) 2013-06-26 EP disclosed
US-20120058347-A1 PLASTIC ARTICLE FOR AUTOMOTIVE GLAZING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
EP-2426175-A1 Plastic article for automotive glazing Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-07 EP disclosed
EP-0822240-B1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS LTD (JP) 2002-09-25 EP disclosed
US-6329456-B1 FOR FORMING A COATING FILM OF HIGH HARDNESS, HEAT RESISTANCE AND WEATHERABILITY MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2001-12-11 US disclosed
US-6090873-A ACRYLATE TERPOLYMER CONTAINING EPOXY AND ALKOXYSILANE GROUPS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2000-07-18 US disclosed
EP-0822240-A1 COATING RESIN COMPOSITION MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1998-02-04 EP disclosed