SCHEMBL93435

SCHEMBL93435

C=C(C)C(=O)OCCC[Si](OC(C)OCC)(OC(C)OCC)OC(C)OCC

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.45
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL71407 0.89 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL73424 0.85 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL133182 0.83 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
Alcohol SCHEMBL29001782 0.82 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1227557 0.82 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28617940 0.82 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6047850 0.82 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL6151602 0.81 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28678325 0.81 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2545645 0.80 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862806-B2 Plastic article for automotive glazing SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-01-09 US disclosed
EP-2607413-B1 Plastic Substrate for Automotive Glazing and Its Repairing Method SHINETSU CHEMICAL CO (JP) 2017-06-21 EP disclosed
EP-2426175-B1 Plastic article for automotive glazing SHINETSU CHEMICAL CO (JP) 2014-07-23 EP disclosed
US-20130164539-A1 PLASTIC SUBSTRATE FOR AUTOMOTIVE GLAZING AND ITS REPAIRING METHOD KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-06-27 US disclosed
EP-2607413-A1 Plastic Substrate for Automotive Glazing and Its Repairing Method Shin-Etsu Chemical Co., Ltd. (JP) 2013-06-26 EP disclosed
US-20120058347-A1 PLASTIC ARTICLE FOR AUTOMOTIVE GLAZING SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 US disclosed
EP-2426175-A1 Plastic article for automotive glazing Shin-Etsu Chemical Co., Ltd. (JP) 2012-03-07 EP disclosed
US-4983699-A Silylated addition polymers with pendant ionic moieties PPG INDUSTRIES, INC. (US) 1991-01-08 US disclosed