Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331551 | 0.82 | TDP1 (0.56) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL33928 | 0.82 | TDP1 (0.56) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL1531678 | 0.82 | TDP1 (0.56) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL1330911 | 0.82 | TDP1 (0.56) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL33927 | 0.82 | TDP1 (0.56) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL7073966 | 0.80 | TDP1 (0.54) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL2584998 | 0.80 | TDP1 (0.54) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| Methane SCHEMBL6442579 | 0.80 | TDP1 (0.54) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| Hydrochloric Acid SCHEMBL10445714 | 0.80 | TDP1 (0.54) | EPHX1EPHX2SMN1; SMN2LMNAATM | |
| SCHEMBL7468986 | 0.80 | TDP1 (0.54) | EPHX1EPHX2SMN1; SMN2LMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593557-A1 | AROMATIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY. | MERCK SHARP & DOHME (GB) | 1994-04-27 | — | — | EP | disclosed |