Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603217 | 0.87 | MEN1 (0.40) | HCAR2MEN1KMT2AS1PR1ALDH1A1 | |
| SCHEMBL11318964 | 0.87 | MEN1 (0.40) | HCAR2MEN1KMT2AS1PR1ALDH1A1 | |
| SCHEMBL19501783 | 0.83 | HCAR2 (0.38) | HCAR2MEN1KMT2AALDH1A1PKM | |
| SCHEMBL17485813 | 0.81 | MEN1 (0.39) | HCAR2MEN1KMT2AALDH1A1PKM | |
| SCHEMBL5276698 | 0.79 | HCAR2 (0.44) | HCAR2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4364997 | 0.78 | MEN1 (0.39) | HCAR2MEN1KMT2AS1PR1ALDH1A1 | |
| SCHEMBL5276881 | 0.77 | HCAR2 (0.42) | HCAR2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5279145 | 0.77 | HCAR2 (0.42) | HCAR2MEN1KMT2ALMNA | |
| SCHEMBL23355495 | 0.77 | — | — | |
| SCHEMBL27338528 | 0.74 | ALDH1A1 (0.34) | HCAR2S1PR1ALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451286-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | Isp Investments Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005806-A1 | 4- AND 5 SUBSTITUTED 1,2,3- TRIAZOLE MOIETIES WITH AT LEAST ONE REMOTE POLYMERIZABLE MOIETY AND POLYMERS THEREOF | ISP INVESTMENTS INC. (US) | 2011-01-13 | — | — | WO | disclosed |