Isoamylamine

Isoamylamine

SCHEMBL9319600

CC(C)CCN.CCCCCN

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.63
MEN1 O00255 1/20 0.63
KMT2A Q03164 1/20 0.63
ALDH1A1 P00352 1/20 0.63
TSHR P16473 1/20 0.63
EPHX1 P07099 1/20 0.63
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 1/20 0.44
GNAI3 P08754 1/20 0.40
GNAO1 P09471 1/20 0.40
GNAI1 P63096 1/20 0.40
DPP7 Q9UHL4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoamylamine SCHEMBL28954758 0.92 DNM1 (0.50) DNM1MEN1KMT2AALDH1A1TSHR
Octane SCHEMBL9464723 0.90 DNM1 (0.65) DNM1MEN1KMT2AALDH1A1TSHR
Dodecylamine SCHEMBL11781677 0.87 DNM1 (0.67) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL28087381 0.84 DNM1 (0.50) DNM1MEN1KMT2AALDH1A1TSHR
Hexadecylamine SCHEMBL8855049 0.82 DNM1 (0.81) DNM1MEN1KMT2AALDH1A1TSHR
Isopropylamine SCHEMBL11609315 0.82 DNM1 (0.71) DNM1MEN1KMT2AALDH1A1TSHR
Isobutane SCHEMBL27489263 0.82 DNM1 (0.77) DNM1MEN1KMT2AALDH1A1TSHR
Hexane SCHEMBL29170825 0.82 DNM1 (0.92) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL7886 0.82
SCHEMBL11498173 0.82 DNM1 (0.92) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349654-B1 AGENT FOR PROPHYLAXIS AND TREATMENT OF PANCREATIC DISEASE OR THE LIKE MITSUI TOATSU CHEMICALS (JP) 1994-01-12 EP disclosed