Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.56 |
| ▸ | CDK4 | P11802 | 4/20 | 0.46 |
| ▸ | CCND1 | P24385 | 4/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082920 | 0.83 | BACE1 (0.56) | BACE1CDK4CCND1 | |
| SCHEMBL30219107 | 0.83 | BACE1 (0.56) | BACE1CDK4CCND1 | |
| SCHEMBL9318861 | 0.83 | BACE1 (0.55) | BACE1CDK4CCND1 | |
| SCHEMBL28566740 | 0.78 | BACE1 (0.69) | BACE1 | |
| SCHEMBL26096587 | 0.76 | BACE1 (0.53) | BACE1CDK4CCND1 | |
| SCHEMBL21507145 | 0.74 | BACE1 (0.64) | BACE1 | |
| SCHEMBL3907028 | 0.74 | BACE1 (0.48) | BACE1CDK4CCND1 | |
| SCHEMBL6434846 | 0.74 | BACE1 (0.51) | BACE1 | |
| SCHEMBL8772163 | 0.74 | CCNB2 (0.44) | BACE1CDK4CCND1CCNB2CDK1 | |
| SCHEMBL6436782 | 0.74 | BACE1 (0.51) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344096-B1 | Leukotriene B4 derivatives, their preparation and use as medicines | SCHERING AG (DE) | 1994-01-05 | — | — | EP | disclosed |
| WO-1989011469-A1 | NEW LEUKOTRIENE-B4-DERIVATES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1989-11-30 | — | — | WO | disclosed |
| EP-0344096-A1 | Leukotriene B4 derivatives, their preparation and use as medicines | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-11-29 | — | — | EP | disclosed |