Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6436782 | 1.00 | BACE1 (0.51) | BACE1CYSLTR2CYSLTR1FAAHEPHX2 | |
| SCHEMBL1715340 | 0.80 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL1715341 | 0.80 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1 | |
| SCHEMBL11127905 | 0.79 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL8700359 | 0.76 | LIPG (0.42) | BACE1 | |
| SCHEMBL9321079 | 0.76 | BACE1 (0.46) | BACE1FAAH | |
| Ether SCHEMBL11047230 | 0.76 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1 | |
| SCHEMBL9318861 | 0.75 | BACE1 (0.55) | BACE1 | |
| SCHEMBL30219107 | 0.75 | BACE1 (0.56) | BACE1 | |
| SCHEMBL2082920 | 0.75 | BACE1 (0.56) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867323-B2 | Cross-coupling reaction of organosilicon nucleophiles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-03-15 | — | — | US | disclosed |
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN | 2002-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183516-A1 | Cross-coupling reaction of organosilicon nucleophiles | TST, HPD, PCNA | BACE1 4535/4885CYSLTR2 2971/4885CYSLTR1 2910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.