Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL125759 | 1.00 | — | — | |
| Nitric Acid SCHEMBL28145851 | 0.96 | — | — | |
| Nitric Acid SCHEMBL28445151 | 0.93 | CA5A (0.57) | CA5ACA5BMEN1KMT2ATSHR | |
| Nitric Acid SCHEMBL2283252 | 0.88 | — | — | |
| Nitric Acid SCHEMBL8193291 | 0.88 | — | — | |
| Nitric Acid SCHEMBL28180072 | 0.87 | CA5A (0.50) | CA5ACA5BTSHRALDH1A1TDP1 | |
| Nitric Acid SCHEMBL29244068 | 0.87 | CA5A (0.50) | CA5ACA5B | |
| Nitric Acid SCHEMBL2734724 | 0.85 | — | — | |
| Nitric Acid SCHEMBL2027210 | 0.82 | — | — | |
| Nitric Acid SCHEMBL7205932 | 0.82 | CA5A (0.80) | CA5ACA5BMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414136-B1 | Water-in-oil type emulsion explosive | NIPPON KAYAKU KK (JP) | 1994-01-05 | — | — | EP | disclosed |
| EP-0317221-B1 | WATER IN OIL TYPE EMULSION EXPLOSIVE | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5000802-A | Water-in-oil type emulsion explosive | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0414136-A2 | Water-in-oil type emulsion explosive | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4908079-A | Continuous phase of low molecular weight polyethylene fuel, dispersive phase of aqueous solution of an inorganic oxidate, emulsifier, foam retainer | NIPPON OIL AND FATS CO., LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0317221-A1 | Water in oil type emulsion explosive | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-05-24 | — | — | EP | disclosed |
| US-4548660-A | POLYMER-CONTAINING OIL; STORAGE STABILITY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-10-22 | — | — | US | disclosed |