SCHEMBL9319963

SCHEMBL9319963

CC(C(N)=O)=C(C(C)C)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9319958 1.00 TDP1 (0.32) TDP1LMNAALOX15BLMPMP22
SCHEMBL6408901 0.78
SCHEMBL6408906 0.78
SCHEMBL9319966 0.76 LMNA (0.32) LMNA
SCHEMBL9319971 0.76 LMNA (0.32) LMNA
SCHEMBL3290789 0.69 LMNA (0.39) TDP1LMNAALOX15BLMPMP22
SCHEMBL15710985 0.69 LMNA (0.39) TDP1LMNAALOX15BLMPMP22
SCHEMBL15710980 0.69 LMNA (0.39) TDP1LMNAALOX15BLMPMP22
SCHEMBL10759619 0.69 LMNA (0.39) TDP1LMNAALOX15BLMPMP22
SCHEMBL2064600 0.69 LMNA (0.39) TDP1LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0428970-B1 Process for preparing aqueous solutions or suspensions of quaternization products of tertiary aminoalkylesters or tertiary aminoalkylamides of acrylic or methacrylic acid, for instance of dimethylaminoethyl-acrylate-methochloride BASF AG (DE) 1994-01-19 EP disclosed
EP-0113038-B1 PROCESS FOR PREPARING CONCENTRATED AQUEOUS SOLUTIONS OF QUATERNIZED PRODUCTS FROM TERTIARY AMINO ALKYL ESTERS OR AMIDES OF ACRYLIC OR METHACRYLIC ACIDS BASF Aktiengesellschaft (DE) 1986-09-10 EP disclosed
US-4520210-A ALKYLATION IN WATER SOLUBLE KETONE THEN SEPARATION BASF AKTIENGESELLSCHAFT (DE) 1985-05-28 US disclosed
EP-0113038-A2 Process for preparing concentrated aqueous solutions of quaternized products from tertiary amino alkyl esters or amides of acrylic or methacrylic acids BASF Aktiengesellschaft (DE) 1984-07-11 EP disclosed