SCHEMBL9320001

SCHEMBL9320001

CCN(CC)c1ccc(C2(c3ccc(N(C)C)cc3)OC(=O)c3cc(N(C)C)ccc32)c(F)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.69
CYP3A4 P08684 5/20 0.69
HPGD P15428 4/20 0.69
HSD17B10 Q99714 3/20 0.69
TDP1 Q9NUW8 3/20 0.69
HIF1A Q16665 1/20 0.69
KMT2A Q03164 6/20 0.57
MEN1 O00255 5/20 0.57
MAPT P10636 4/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
MAPK1 P28482 1/20 0.36
DHFR P00374 2/20 0.34
CYP19A1 P11511 1/20 0.34
POLB P06746 2/20 0.33
LMNA P02545 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CFTR P13569 1/20 0.33
GOPC Q9HD26 1/20 0.33
ESR1 P03372 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536831 0.91 ALDH1A1 (0.80) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL3176397 0.89 ALDH1A1 (0.82) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL8322552 0.89 ALDH1A1 (0.78) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL29384978 0.89 ALDH1A1 (0.69) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL28008 0.89 ALDH1A1 (0.69) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL9319662 0.89 ALDH1A1 (0.69) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL9319300 0.89 ALDH1A1 (0.69) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL1369193 0.88 ALDH1A1 (0.80) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL9321295 0.88 ALDH1A1 (0.67) ALDH1A1CYP3A4HPGDHSD17B10TDP1
SCHEMBL28977116 0.88 ALDH1A1 (0.67) ALDH1A1CYP3A4HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0349194-B1 Heat-sensitive record material KANZAKI PAPER MFG CO LTD (JP) 1994-01-05 EP disclosed
US-4977132-A CONTAINING FLUORAN DERIVATIVE, PHTHALIDE DERIVATIVE, PHENOLIC COMPOUND; STORAGE STABILITY KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-12-11 US disclosed
EP-0349194-A2 Heat-sensitive record material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-01-03 EP disclosed