SCHEMBL9320469

SCHEMBL9320469

O=C(Nc1ccc([N+](=O)[O-])cc1)n1sccc1=O

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.53
MEN1 O00255 8/20 0.53
GAA P10253 2/20 0.52
POLB P06746 2/20 0.47
TGM2 P21980 1/20 0.47
RAB9A P51151 4/20 0.46
MAPT P10636 3/20 0.46
MAPK1 P28482 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
NPC1 O15118 3/20 0.46
NAMPT P43490 1/20 0.46
MITF O75030 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MYOC Q99972 1/20 0.46
LMNA P02545 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322082 0.84 KMT2A (0.57) KMT2AMEN1GAAPOLBRAB9A
SCHEMBL28813844 0.72 GAA (0.85) KMT2AMEN1GAARAB9AMAPT
SCHEMBL9320475 0.71 KMT2A (0.53) KMT2AMEN1GAAPOLBTGM2
SCHEMBL1177730 0.70 MEN1 (1.00) KMT2AMEN1GAAPOLBTGM2
SCHEMBL6302157 0.70 MEN1 (1.00) KMT2AMEN1GAAPOLBTGM2
SCHEMBL9771580 0.70 GAA (0.55) KMT2AMEN1GAAPOLBTGM2
SCHEMBL14574134 0.70 GAA (0.97) KMT2AMEN1GAATGM2RAB9A
SCHEMBL3189929 0.70 KMT2A (0.69) KMT2AMEN1GAAPOLBTGM2
SCHEMBL9132516 0.70 ALOX5 (0.50) KMT2AMEN1GAAPOLBMAPT
SCHEMBL14574146 0.70 GAA (0.74) KMT2AMEN1GAAPOLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331319-B1 Method for the formation of images KONISHIROKU PHOTO IND (JP) 1994-01-26 EP disclosed
US-H1090-H High contrast; hydrazide, isothizolone, bromonitroalcohol KONICA CORPORATION (JP) 1992-08-04 US disclosed
EP-0356801-A1 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1990-03-07 EP disclosed
EP-0331319-A1 Method for the formation of images KONICA CORPORATION (JP) 1989-09-06 EP disclosed
EP-0090584-B1 LIGHT-SENSITIVE SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1986-12-03 EP disclosed
US-4490462-A CONTAINING ISOTHIAZOLIN-3-ONE MICROBIOCIDE OR FUNGICIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-12-25 US disclosed
EP-0090584-A2 Light-sensitive silver halide photographic material KONICA CORPORATION (JP) 1983-10-05 EP disclosed