Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.61 |
| ▸ | TOP1 | P11387 | 1/20 | 0.59 |
| ▸ | TOP2A | P11388 | 1/20 | 0.59 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23340185 | 0.87 | HDAC1 (0.70) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL8403312 | 0.86 | HDAC1 (0.79) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL18361216 | 0.84 | HDAC1 (0.77) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL23888859 | 0.84 | HDAC1 (0.71) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL8401704 | 0.83 | HDAC1 (0.89) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL407834 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL30363156 | 0.82 | HDAC1 (1.00) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL18063662 | 0.80 | TOP1 (0.59) | TOP1TOP2ATOP2BRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL2828661 | 0.80 | HDAC1 (0.96) | HDAC1HDAC2HDAC3MAPK1NCOR2 | |
| SCHEMBL23500763 | 0.80 | HDAC1 (0.75) | HDAC1HDAC2HDAC3MAPK1NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2308816-A | — | — | None | — | — | JP | disclosed |
| JP-3250048-A | — | — | None | — | — | JP | disclosed |
| EP-0387106-B1 | Novel diamine compounds, production of the same and polyamideimide resins produced therefrom | TOMOEGAWA PAPER CO LTD (JP) | 1994-02-02 | — | — | EP | disclosed |
| JP-H03250048-A | POSITIVE TYPE PHOTOSENSITIVE POLYAMIDEIMIDE COMPOSITION | TOMOEGAWA PAPER CO LTD | 1991-11-07 | — | — | JP | disclosed |
| US-5019642-A | Novel diamine compounds, production of the same and polyamideimide resins produced therefrom | TOMOEGAWA PAPER CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| JP-H02308816-A | POLYAMIDE-IMIDE RESIN | TOMOEGAWA PAPER CO LTD | 1990-12-21 | — | — | JP | disclosed |
| EP-0387106-A1 | Novel diamine compounds, production of the same and polyamideimide resins produced therefrom | TOMOEGAWA PAPER CO. LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |