⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600335 | 0.86 | — | — | |
| SCHEMBL27617920 | 0.76 | — | — | |
| SCHEMBL25045691 | 0.70 | — | — | |
| SCHEMBL20161408 | 0.70 | ROCK2 (0.34) | — | |
| SCHEMBL12570741 | 0.69 | — | — | |
| SCHEMBL634065 | 0.69 | — | — | |
| SCHEMBL18643924 | 0.67 | — | — | |
| SCHEMBL11317907 | 0.67 | — | — | |
| SCHEMBL26019779 | 0.67 | — | — | |
| SCHEMBL24157966 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045206-B2 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2023-02-15 | — | — | EP | disclosed |
| WO-2020081829-A1 | TREATMENT OF ACANTHAMOEBA OR BALAMUTHIA TROPHOZOITES AND/OR CYSTS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2020-04-23 | — | — | WO | disclosed |
| EP-0406160-B1 | Primer | CIBA GEIGY AG (CH) | 1994-02-02 | — | — | EP | disclosed |
| US-5166383-A | Promoters for adhesion, moisture curing polyurethanes | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0406160-A2 | Primer | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |
| US-4404379-A | REACTING A 2 RING-NITROGEN-CONTAINING HETEROCYCLIC COMPOUND WITH A POLYISOCYANATE; STORAGE STABILITY; POLYMERIC HARDENERS | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | disclosed |
| EP-0001065-B1 | CYCLOAMINALS, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | BAYER AG (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0001065-A1 | Cycloaminals, process for their preparation and their application | BAYER AG (DE) | 1979-03-21 | — | — | EP | disclosed |