Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.53 |
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | RARG | P13631 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | GOT1 | P17174 | 1/20 | 0.52 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460115 | 0.91 | RARA (0.53) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8458811 | 0.89 | RARA (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL5078203 | 0.85 | RARA (0.65) | RARARARBRARGMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9737093 | 0.84 | RARA (0.64) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9320719 | 0.82 | RARA (0.52) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8521998 | 0.78 | RARA (0.53) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9492172 | 0.78 | RARA (0.62) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8523165 | 0.77 | RARA (0.57) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL8426342 | 0.77 | RARA (0.60) | RARARARBRARGMEN1KMT2A | |
| SCHEMBL9737080 | 0.76 | RARA (0.53) | RARARARBRARGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409729-B1 | Bi-aromatic thioesters, process for their preparation and their use in human or veterinary medicine and in cosmetics | CIRD GALDERMA (FR) | 1994-01-12 | — | — | EP | claimed |