Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.89 |
| ▸ | RAB9A | P51151 | 2/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.75 |
| ▸ | HPGD | P15428 | 5/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.75 |
| ▸ | PGR | P06401 | 2/20 | 0.75 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.75 |
| ▸ | AR | P10275 | 1/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900821 | 1.00 | NPC1 (0.89) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL1348833 | 1.00 | NPC1 (0.89) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL29419872 | 1.00 | NPC1 (0.89) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL1514997 | 0.94 | NPC1 (1.00) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL29365072 | 0.94 | NPC1 (1.00) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL38652 | 0.94 | NPC1 (1.00) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL10453973 | 0.92 | NPC1 (0.96) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL29380756 | 0.92 | NPC1 (0.96) | NPC1RAB9ACYP3A4HPGDLMNA | |
| SCHEMBL2526579 | 0.92 | NPC1 (0.96) | NPC1RAB9ACYP3A4HPGDLMNA | |
| Dioxybenzone SCHEMBL5011376 | 0.92 | HPGD (0.91) | NPC1RAB9ACYP3A4HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10619098-B2 | Ultraviolet light absorbers | TRANSITIONS OPTICAL, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| EP-3201292-B1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL INC (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2428540-B1 | Coating composition | SHINETSU CHEMICAL CO (JP) | 2018-02-21 | — | — | EP | disclosed |
| US-9862806-B2 | Plastic article for automotive glazing | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-3201292-A1 | ULTRAVIOLET LIGHT ABSORBERS | Transitions Optical, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2607413-B1 | Plastic Substrate for Automotive Glazing and Its Repairing Method | SHINETSU CHEMICAL CO (JP) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016053662-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. (US) | 2016-04-07 | — | — | WO | disclosed |
| EP-2426175-B1 | Plastic article for automotive glazing | SHINETSU CHEMICAL CO (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8642672-B2 | Coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20120059080-A1 | COATING COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| EP-2426175-A1 | Plastic article for automotive glazing | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |
| EP-2300599-A4 | AUGMENTATION OF CELL THERAPY EFFICACY INCLUDING TREATMENT WITH ALPHA 1-3 FUCOSLYTRANSFERASE | AMERICAN STEM CELL INC (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8052900-B2 | Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-11-08 | — | — | US | disclosed |
| EP-2182032-B1 | Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function | SHINETSU CHEMICAL CO (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20100108960-A1 | REACTIVE UV ABSORBER, UV-SCREEN FILM-FORMING CURABLE COATING SOLUTION, UV-SCREEN FILM, AND SUBSTRATE HAVING UV-SCREENING FUNCTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
| EP-2182032-A1 | Reactive UV absorber, UV-screen film-forming curable coating solution, UV-screen film, and substrate having UV-screening function | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-4525504-A | 1,4-CYCLOHEXANDEICARBOXYLIC ACID AND 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL, UV AND HINDERED AMINE STABILIZERS | EASTMAN KODAK COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
| US-4524165-A | 1,4-CYCLOHEXANEDICARBOXYLIC ACID AND 1,4-CYCLOHEXANE DIOL MONOMERS; POLYALKYLENE GLCOLS; STABILIZER MIXTURE | EASTMAN KODAK COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4323710-A | A NONAQUEOUS SOLVENT OF POLYOXYETHYLENE GLYCOL OR ITS ALKYLATED DERIVATIVES | GAF CORPORATION (US) | 1982-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619098-B2 | Ultraviolet light absorbers | ERCC1, MCM4, ERCC4 | NPC1 1292/4885RAB9A 3167/4885CYP3A4 189/4885 |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | MCM4, ERCC1, ERCC4 | NPC1 939/4885RAB9A 3917/4885CYP3A4 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.