Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.91 |
| ▸ | LMNA | P02545 | 4/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.91 |
| ▸ | PGR | P06401 | 2/20 | 0.91 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.91 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.91 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.91 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.91 |
| ▸ | AR | P10275 | 1/20 | 0.91 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.91 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.91 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.91 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.91 |
| ▸ | NPC1 | O15118 | 5/20 | 0.75 |
| ▸ | RAB9A | P51151 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dioxybenzone SCHEMBL29364693 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL7936480 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL15894 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL6674075 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL29365575 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL29354139 | 0.95 | LMNA (1.00) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL22042270 | 0.93 | HPGD (0.81) | HPGDCYP3A4LMNACYP1A2PGR | |
| Dioxybenzone SCHEMBL20641426 | 0.92 | LMNA (0.94) | HPGDCYP3A4LMNACYP1A2PGR | |
| SCHEMBL93206 | 0.92 | NPC1 (0.89) | HPGDCYP3A4LMNACYP1A2PGR | |
| SCHEMBL30900821 | 0.92 | NPC1 (0.89) | HPGDCYP3A4LMNACYP1A2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999195-A1 | METHOD FOR INCORPORATING ADDITIVES INTO POLYMERS | Ciba Holding Inc. (CH) | 2008-12-10 | — | — | EP | claimed |
| WO-2007110324-A1 | METHOD FOR INCORPORATING ADDITIVES INTO POLYMERS | CIBA HOLDING INC. (CH) | 2007-10-04 | — | — | WO | claimed |